Monday, June 10, 2013

Study shows cardiac MRI use reduces adverse events for patients with acute chest pain

Study shows cardiac MRI use reduces adverse events for patients with acute chest pain [ Back to EurekAlert! ] Public release date: 10-Jun-2013
[ | E-mail | Share Share ]

Contact: Bonnie Davis
bdavis@wakehealth.edu
336-716-4977
Wake Forest Baptist Medical Center

WINSTON-SALEM, N.C. June 10, 2013 Wake Forest Baptist Medical Center doctors have found that using stress cardiac magnetic resonance (CMR) imaging in an Emergency Department observation unit to care for patients with acute chest pain is a win-win for the patient and the institution.

In a small, single-center clinical trial, Chadwick Miller, M.D., M.S., and colleagues found that evaluating older, more complex patients in the observation unit with stress cardiac MRI, as opposed to usual inpatient care, reduced hospital readmissions, coronary revascularization procedures and the need for additional cardiac testing.

The observation unit is an area of the Emergency Department designed for short stays longer than a typical ED visit, said Miller, but shorter than a hospital admission. Cardiac MRI is a type of heart testing that uses magnetic forces to capture pictures of the heart.

"We were looking at the optimum way to evaluate people with chest pain and focusing on those patients who are generally older, have many risk factors for coronary disease or may have had prior health problems, basically the intermediate to higher risk population," Miller said. "At most hospitals in the United States, after evaluation in the emergency department, these patients are admitted to the hospital to complete their care."

The study appears online this month ahead of print in the journal JACC: Cardiovascular Imaging.

Miller, who serves as director of clinical research and executive vice-chair of Emergency Medicine at Wake Forest Baptist, said the study built on previous research findings that more complex patients managed in an observation unit with stress CMR testing experienced a reduction in care costs of about $2,100 per patient per year. For the new study, the researchers wanted to specifically look at three care events: coronary revascularization, hospital readmissions and additional heart testing.

The researchers recruited 105 patients from Wake Forest Baptist's Emergency Department, randomizing them to receive care either in the Observation Unit with CMR or in the hospital. The patients were followed for 90 days, after which the researchers found significant reductions in coronary revascularization procedures, fewer hospital readmissions and fewer recurrent cardiac testing episodes or the need for additional testing.

"What's exciting about this is not only can we reduce events that are important to patients, but we can reduce costs as well," Miller said. "What we think is happening is that the cardiac MRI is more accurately selecting patients who will benefit the most from having invasive procedures done. It's a win-win."

The single-center design of the study is a limitation, Miller said, and these findings need to be replicated across multiple centers to validate the findings.

###

The study was funded by National Institutes of Health's National Heart, Lung, and Blood Institute, grant 1 R21HL097131-01A1; 1 R01HL076438, NIH T-32 HL087730.

Co-authors include: L. Douglas Case, Ph.D., William C. Little, M.D., Simon A. Mahler, M.D., Gregory L. Burke, M.D., MSc., Erin N. Harper, B.S., Cedric Lefebvre, M.D., Brian Hiestand, M.D., M.P.H., James W. Hoekstra, M.D., Craig A. Hamilton, Ph.D., W. Gregory Hundley, M.D., all of Wake Forest Baptist.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Study shows cardiac MRI use reduces adverse events for patients with acute chest pain [ Back to EurekAlert! ] Public release date: 10-Jun-2013
[ | E-mail | Share Share ]

Contact: Bonnie Davis
bdavis@wakehealth.edu
336-716-4977
Wake Forest Baptist Medical Center

WINSTON-SALEM, N.C. June 10, 2013 Wake Forest Baptist Medical Center doctors have found that using stress cardiac magnetic resonance (CMR) imaging in an Emergency Department observation unit to care for patients with acute chest pain is a win-win for the patient and the institution.

In a small, single-center clinical trial, Chadwick Miller, M.D., M.S., and colleagues found that evaluating older, more complex patients in the observation unit with stress cardiac MRI, as opposed to usual inpatient care, reduced hospital readmissions, coronary revascularization procedures and the need for additional cardiac testing.

The observation unit is an area of the Emergency Department designed for short stays longer than a typical ED visit, said Miller, but shorter than a hospital admission. Cardiac MRI is a type of heart testing that uses magnetic forces to capture pictures of the heart.

"We were looking at the optimum way to evaluate people with chest pain and focusing on those patients who are generally older, have many risk factors for coronary disease or may have had prior health problems, basically the intermediate to higher risk population," Miller said. "At most hospitals in the United States, after evaluation in the emergency department, these patients are admitted to the hospital to complete their care."

The study appears online this month ahead of print in the journal JACC: Cardiovascular Imaging.

Miller, who serves as director of clinical research and executive vice-chair of Emergency Medicine at Wake Forest Baptist, said the study built on previous research findings that more complex patients managed in an observation unit with stress CMR testing experienced a reduction in care costs of about $2,100 per patient per year. For the new study, the researchers wanted to specifically look at three care events: coronary revascularization, hospital readmissions and additional heart testing.

The researchers recruited 105 patients from Wake Forest Baptist's Emergency Department, randomizing them to receive care either in the Observation Unit with CMR or in the hospital. The patients were followed for 90 days, after which the researchers found significant reductions in coronary revascularization procedures, fewer hospital readmissions and fewer recurrent cardiac testing episodes or the need for additional testing.

"What's exciting about this is not only can we reduce events that are important to patients, but we can reduce costs as well," Miller said. "What we think is happening is that the cardiac MRI is more accurately selecting patients who will benefit the most from having invasive procedures done. It's a win-win."

The single-center design of the study is a limitation, Miller said, and these findings need to be replicated across multiple centers to validate the findings.

###

The study was funded by National Institutes of Health's National Heart, Lung, and Blood Institute, grant 1 R21HL097131-01A1; 1 R01HL076438, NIH T-32 HL087730.

Co-authors include: L. Douglas Case, Ph.D., William C. Little, M.D., Simon A. Mahler, M.D., Gregory L. Burke, M.D., MSc., Erin N. Harper, B.S., Cedric Lefebvre, M.D., Brian Hiestand, M.D., M.P.H., James W. Hoekstra, M.D., Craig A. Hamilton, Ph.D., W. Gregory Hundley, M.D., all of Wake Forest Baptist.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2013-06/wfbm-ssc061013.php

gordon hayward gas prices rising stars challenge star trek 2 kathy ireland brooke mueller all star weekend

Tuesday, May 7, 2013

Obama dares graduates to reject cynical voices

President Barack Obama arrives at the Ohio State University spring commencement in the Ohio Stadium, Sunday, May 5, 2013, in Columbus, Ohio. Obama is the third sitting president to give the commencement speech at Ohio State University. At left is Annie Leibovitz. (AP Photo/Carolyn Kaster)

President Barack Obama arrives at the Ohio State University spring commencement in the Ohio Stadium, Sunday, May 5, 2013, in Columbus, Ohio. Obama is the third sitting president to give the commencement speech at Ohio State University. At left is Annie Leibovitz. (AP Photo/Carolyn Kaster)

President Barack Obama and Ohio State University President E. Gordon Gee arrive at the Ohio State University spring commencement in the Ohio Stadium, Sunday, May 5, 2013, in Columbus, Ohio. Obama is the third sitting president to give the commencement speech at Ohio State University. (AP Photo/Carolyn Kaster)

President Barack Obama greets people waiting for him on the tarmac as he arrives on Air Force One at Rickenbacker International Airport, Sunday, May 5, 2013, in Columbus, Ohio, en route to speak at the Ohio State University spring commencement. (AP Photo/Carolyn Kaster)

President Barack Obama laughs as he walks to board Air Force One, Sunday, May 5, 2013, in Andrews Air Force Base, Md., en route to speak at the Ohio State University spring commencement, in Columbus, Ohio. (AP Photo/Carolyn Kaster)

COLUMBUS, Ohio (AP) ? A year to the day after kicking off his victorious re-election campaign on this college campus, President Barack Obama returned to Ohio State University and told graduates that only through vigorous participation in their democracy can they right an ill-functioning government and break through relentless cynicism about the nation's future.

"I dare you, Class of 2013, to do better. I dare you to dream bigger," Obama said.

In a sunbaked stadium filled with more than 57,000 students, friends and relatives, Obama lamented an American political system that gets consumed by "small things" and works for the benefit of society's elite. He called graduates to duty to "accomplish great things," like rebuilding a still-feeble economy and fighting poverty and climate change.

"Only you can ultimately break that cycle. Only you can make sure the democracy you inherit is as good as we know it can be," Obama told more than 10,000 cap-and-gown-clad graduates gathered for the rite of passage. "But it requires your dedicated, informed and engaged citizenship."

The visit to Ohio State ? the first of three commencement addresses Obama will give this season ? was a homecoming of sorts for Obama, who has visited the campus five times over little more than a year, starting with his first official campaign rally here last May. He made many more stops elsewhere in Ohio as he and Republican Mitt Romney dueled for the Buckeye State, and its 18 electoral votes were pivotal to Obama's victories in both 2008 and 2012.

There was little direct mention of party politics Sunday, but ample allusion to the partisan battles that cramped many of Obama's legislative efforts in his first term and have continued unabated into his second.

In an apparent reference to his failed push on gun control, he bemoaned that a small minority in Congress find excuses to oppose things that most Americans support.

"This is a joyous occasion, so let me put it charitably: I think it's fair to say our democracy isn't working as well as we know it can," Obama said.

Invoking the end of the Cold War, 9/11 and the economic recession, Obama said this generation had been tested beyond what their parents could have imagined. But he said young Americans have responded with a deep commitment to service and a conviction that they can improve their surroundings. He urged graduates to run for office, start a business or join a cause, contending that the health of their democracy "requires your dedicated, informed and engaged citizenship."

"You've grown up hearing voices that incessantly warn of government as nothing more than some separate, sinister entity that's at the root of all our problems," Obama said. "You should reject these voices. Because what these suggest is that somehow our brave, creative, unique experiment in self-rule is just a sham with which we can't be trusted."

Among the 10,143 students receiving diplomas at this sprawling state university Sunday were 130 veterans, including the first class to benefit from the new GI Bill that Congress passed after 9/11, university officials said.

Ohio State also bestowed an honorary doctorate on Obama, applauding his "unwavering belief in the ability to unite people around a politics of purpose." Also honored was photographer Annie Leibovitz, whose images of Obama and his family have become iconic reflections on the nation's first black president.

Obama's other two commencement speeches this season will be later in May at the U.S. Naval Academy in Annapolis, Md., and at Morehouse College, an all-male school in Atlanta.

___

Follow Josh Lederman on Twitter: http://twitter.com/joshledermanAP

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/386c25518f464186bf7a2ac026580ce7/Article_2013-05-05-US-Obama/id-bbea54f334ad4913b06651e7b6fdb08b

whitney houston dead 2012 whitney houston passed away heartbreak hotel don cornelius whitney houston i will always love you breaking news whitney houston carmen

Possible treatment for serious blood cancer

Possible treatment for serious blood cancer [ Back to EurekAlert! ] Public release date: 6-May-2013
[ | E-mail | Share Share ]

Contact: Markus Hansson
markus.hansson@med.lu.se
46-705-931-110
Lund University

A single antibody could be the key to treating multiple myeloma, or cancer of the blood, currently without cure or long-term treatment.

"We tested the antibody in various ways, including on tumour cells from myeloma patients that have been transplanted into mice. The tests showed that the antibody is able to destroy myeloma cells", explains Markus Hansson, a researcher at Lund University in Sweden.

Using a 'biological library' of thousands of antibodies from the company BioInvent in Lund, the team singled out antibody BI-505, shown to have a powerful effect on the tumour cells in both cell studies and animal experiments. It has also been tested in an initial safety study on seriously ill patients, and a study of its treatment effects has just started.

"This study will include patients who have just been diagnosed and therefore still feel fairly well. We want to test the antibody treatment before the patients are treated with any other drugs", says Markus Hansson.

Today there are a number of drugs to treat multiple myeloma, but no cure. None of the drugs are able to eradicate the disease, meaning cancer cells increase in number after a period of remission. Survival has been extended with new treatments, but less than half of all patients live longer than five years from diagnosis.

Myeloma occurs when a specific type of cell in the bone marrow is converted into tumour cells. Blood formation is disrupted and patients suffer from a lack of blood resulting in fatigue. The bones can be weakened with a risk of fractures and compacted vertebrae, and patients sometimes suffer kidney failure as a result of the disease.

Antibodies are a part of the immune system, fighting off foreign bodies. Antibody-based drugs are now used to treat certain inflammatory diseases and types of cancer.

The treatment study in Lund will involve 15 patients and is expected to be completed this year. If the results are good, Markus Hansson and his colleagues hope to be able to continue testing BI-505 in larger-scale studies. They will be studying the best way of using the new antibody: alone or in combination with other drugs; at the start of the disease or at a later stage.

###


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Possible treatment for serious blood cancer [ Back to EurekAlert! ] Public release date: 6-May-2013
[ | E-mail | Share Share ]

Contact: Markus Hansson
markus.hansson@med.lu.se
46-705-931-110
Lund University

A single antibody could be the key to treating multiple myeloma, or cancer of the blood, currently without cure or long-term treatment.

"We tested the antibody in various ways, including on tumour cells from myeloma patients that have been transplanted into mice. The tests showed that the antibody is able to destroy myeloma cells", explains Markus Hansson, a researcher at Lund University in Sweden.

Using a 'biological library' of thousands of antibodies from the company BioInvent in Lund, the team singled out antibody BI-505, shown to have a powerful effect on the tumour cells in both cell studies and animal experiments. It has also been tested in an initial safety study on seriously ill patients, and a study of its treatment effects has just started.

"This study will include patients who have just been diagnosed and therefore still feel fairly well. We want to test the antibody treatment before the patients are treated with any other drugs", says Markus Hansson.

Today there are a number of drugs to treat multiple myeloma, but no cure. None of the drugs are able to eradicate the disease, meaning cancer cells increase in number after a period of remission. Survival has been extended with new treatments, but less than half of all patients live longer than five years from diagnosis.

Myeloma occurs when a specific type of cell in the bone marrow is converted into tumour cells. Blood formation is disrupted and patients suffer from a lack of blood resulting in fatigue. The bones can be weakened with a risk of fractures and compacted vertebrae, and patients sometimes suffer kidney failure as a result of the disease.

Antibodies are a part of the immune system, fighting off foreign bodies. Antibody-based drugs are now used to treat certain inflammatory diseases and types of cancer.

The treatment study in Lund will involve 15 patients and is expected to be completed this year. If the results are good, Markus Hansson and his colleagues hope to be able to continue testing BI-505 in larger-scale studies. They will be studying the best way of using the new antibody: alone or in combination with other drugs; at the start of the disease or at a later stage.

###


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2013-05/lu-ptf050613.php

Jennifer Granholm Tulane player injured fox sports obama speech Art Modell Frank Ocean Gay bill clinton

Holly Madison Planning a ?Kardashian-Sized? Family

"We want a huge family, like a Kardashian-sized family," she tells PEOPLE Saturday at TAO Beach's season opening. "I want to have three, then wait a few years for them to be older, then have another three."

Source: http://feeds.celebritybabies.com/~r/celebrity-babies/~3/l8mbxrsHOvE/

sheryl sandberg superbowl recipes super bowl kick off chili recipes carlos condit diaz vs condit super bowl 2012 kickoff time

Mercedes-Benz Becomes Main Automotive Sponsor for Mille Miglia ...

Mercedes Benz Becomes Main Automotive Sponsor for Mille Miglia Event Mercedes Benz Becomes Main Automotive Sponsor for Mille Miglia Event

In order to establish a ?long-term collaboration,? Mercedes-benz Classic and 1000 Miglia S.R.L., the entity behind Mille Miglia endurance race, have struck a partnership that will see Mercedes-Benz become the main automotive sponsor for the event.

As expected because of the company?s extensive participation in the event throughout its history, Mercedes-Benz will be fielding a number of vehicles in this year?s iteration of the Mille Miglia. Some Mercedes-Benz brand ambassadors will also be present and will participate, including former F1 drivers David Coulthard, Karl Wendlinger, and Jochen Mass. The driver of the F1 Safety Car (which is a Mercedes SLS AMG), Bernd Maylander, will also be there.

Mille Miglia 2013 will take the participants from Brescia, a town in northern Italy, all the way to Rome, and then back again to the starting point. That?s a course that makes up a thousand miles, giving the event its name. Along the way, the classic cars driven by the participants will encounter different challenges.

The Mille Miglia only accepts cars that were among the original line-up for the historic event (1927-1957), making it a true showcase of classic cars in the modern era. That also makes it the perfect event for Mercedes-Benz Classic to partner up with.

Source: http://www.benzinsider.com/2013/05/mercedes-benz-mille-miglia/

transcendentalism bells palsy channel 5 news uc berkeley harrison barnes brett ratner stevie nicks

Saturday, May 4, 2013

Brooke Mueller?s Twin Sons Taken Away Over Drug Use

Brooke Mueller’s Twin Sons Taken Away Over Drug Use

Brooke Mueller still cracked outLos Angeles County’s Department of Children and Family Services have removed Charlie Sheen and Brooke Mueller’s twin sons, Bob and Max, from Brooke’s care due to her drug use. Charlie’s other ex-wife, Denise Richards, has been awarded temporary custody of the boys. Social workers removed the children from Brooke Mueller’s care because of claims the ...

Brooke Mueller’s Twin Sons Taken Away Over Drug Use Stupid Celebrities Gossip Stupid Celebrities Gossip News

Source: http://stupidcelebrities.net/2013/05/brooke-muellers-twin-sons-taken-away-over-drug-use/

anna paquin warren buffett 2012 nfl schedule dishonored april 18 delonte west vanessa williams

May snowstorm rumbles on over Plains, Upper Midwest

The middle of the country is experiencing May snowfall records in what seems to be a never-ending winter. The Weather Channel's Mike Seidel reports.

By Ian Johnston, Staff Writer, NBC News

A rare May snowstorm that's hit the Plains and Upper Midwest was expected to continue into Friday and even Saturday in places, the National Weather Service said.

However, it added that the ?rather unusual weather pattern? was ?beginning to abate over the Upper Midwest.?

A number of winter storm advisories were in place early Friday for parts of Missouri, Montana, Michigan, Wisconsin, Minnesota, Iowa, Wyoming, and Oklahoma.

The worst affected areas in the mainland U.S. -- southern Montana and northern Wyoming -- could see 5 to 9 inches of snow from Friday morning to the time it finally stops early Saturday evening.

The weather service said the other areas could see anything from freezing rain and sleet in northwestern Michigan to up to 3 inches of snow in northeastern Oklahoma.

There was also a winter weather notice for Alaska, where Denali National Park and other areas could see up to 10 inches of snow.

The weather service said ?widespread showers and thunderstorms? were expected to develop over the Deep South and into Florida through the end of the week.

?Rainfall amounts of several inches are possible where heavy rain persists the longest,? it said.

On Thursday, weather.com reported that the storm had "dumped up to 13 inches of snow in Owatonna, Minn.,? while up to 14 inches of snow was measured in Ellsworth, Wis. Up to nine inches fell in Dodge County, Minn., on Thursday.

In some parts of the country, spring still feels far away. The snowfall in the Rockies, Plains and Dakotas is setting records and may not end until Friday. NBC's Brian Williams reports

?This is a record for me,? Brian Wagstrom, director of public works in Minnetonka, Minn., told NBC station KARE. ?This is the latest that we have ever put plows on this time of the year.?

Jim Eulberg, director of public works in the South Dakota town of Worthington, had to tell his crews to give up spring street sweeping and ready the plows.

?When you?re looking at the calendar, you?re thinking this is the stuff we should be doing. Not dealing with ice storm damage and plowing,? Eulberg told NBC station KDLT.

NBC News' Matthew DeLuca contributed to this report.

Related:

This story was originally published on

Source: http://feeds.nbcnews.com/c/35002/f/653381/s/2b778f4e/l/0Lusnews0Bnbcnews0N0C0Inews0C20A130C0A50C0A30C180A33780A0Emay0Esnowstorm0Erumbles0Eon0Eover0Eplains0Eupper0Emidwest0Dlite/story01.htm

Suspects in Boston Bombing Kerry Rhodes Daft Punk Get Lucky Texas explosion Paul Kevin Curtis man of steel man of steel